Unnamed: 0 int64 0 14.2k | ReviewID int64 2.14M 32.7M | Target stringlengths 12 3.68k | Background stringlengths 46 5.35k ⌀ | Abstract stringlengths 263 730k ⌀ |
|---|---|---|---|---|
0 | 30,760,312 | Conclusions SC therapy is effective for PAH in pre clinical studies .
These results may help to st and ardise pre clinical animal studies and provide a theoretical basis for clinical trial design in the future . | Background Despite significant progress in drug treatment , the prognosis of patients with advanced pulmonary arterial hypertension ( PAH ) remains extremely poor .
Many pre clinical studies have reported the efficacy of stem cell ( SC ) therapy for PAH ; however , this approach remains controversial .
The aim of this ... | Although transplantation of adult bone marrow mesenchymal stem cells ( BM-MSCs ) holds promise in the treatment for pulmonary arterial hypertension ( PAH ) , the poor survival and differentiation potential of adult BM-MSCs have limited their therapeutic efficiency . Here , we compared the therapeutic efficacy of human ... |
1 | 19,588,356 | There was a trend for endothelin receptor antagonists to reduce mortality ( OR 0.48 ; 95 % CI 0.21 to 1.09 ) , and limited data suggest that endothelin receptor antagonists improve Borg dyspnoea score and cardiopulmonary haemodynamics in symptomatic patients .
Hepatic toxicity was not common , and endothelin receptor a... | BACKGROUND Pulmonary arterial hypertension is a devastating disease , which leads to right heart failure and premature death .
Recent evidence suggests that endothelin receptor antagonists may be promising drugs in the treatment of pulmonary arterial hypertension .
OBJECTIVES To evaluate the efficacy of endothelin rece... | BACKGROUND Primary pulmonary hypertension is a progressive disease for which no treatment has been shown in a prospect i ve , r and omized trial to improve survival . METHODS We conducted a 12-week prospect i ve , r and omized , multicenter open trial comparing the effects of the continuous intravenous infusion of epop... |
2 | 23,893,797 | This present meta- analysis suggests that statin pretreatment might be effective in improving myocardial perfusion in STEMI patients | BACKGROUND To achieve sufficient myocardial perfusion in ST-segment elevation myocardial infa rct ion ( STEMI ) patients receiving primary percutaneous coronary intervention ( PPCI ) , many adjunctive therapies have been proposed .
Previous trials have reported variances in myocardial perfusion improvement for statin p... | BACKGROUND Although improved epicardial blood flow ( as assessed with either TIMI flow grade s or TIMI frame count ) has been related to reduced mortality after administration of thrombolytic drugs , the relationship of myocardial perfusion ( as assessed on the coronary arteriogram ) to mortality has not been examined ... |
3 | 27,167,891 | In conclusion , there is a lack of evidence of effectiveness for most waterpipe interventions . | Waterpipe tobacco smoking is growing in popularity despite adverse health effects among users .
We systematic ally review ed the literature , search ing MEDLINE , EMBASE and Web of Science , for interventions targeting prevention and cessation of waterpipe tobacco smoking . | INTRODUCTION We explored the differential effect of cessation interventions ( behavioral support sessions with [ BSS+ ] and without [ BSS ] bupropion ) between hookah and cigarette smokers . METHODS We reanalyzed the data from a major cluster-r and omized controlled trial , ASSIST ( Action to Stop Smoking In Suspected ... |
4 | 28,753,768 | Several PROMs have been identified to evaluate sexual function in neurologic patients .
Strong evidence was found only for the Multiple Sclerosis Intimacy and Sexuality Question naire-15 and Multiple Sclerosis Intimacy and Sexuality Question naire-19 for patients with MS , although evidence was lacking for certain meas... | CONTEXT Impaired sexual function has a significant effect on quality of life .
Various patient-reported outcome measures ( PROMs ) are available to evaluate sexual function .
The quality of the PROMs to be used for neurologic patients remains unknown .
OBJECTIVE To systematic ally review which vali date d PROMs are ava... | INTRODUCTION Cultural sensitivities tend to limit assessment s of sexual dysfunction ( SD ) in Parkinson 's disease ( PD ) . OBJECTIVE To assess the validity and reliability of the Thai translation ( ASEX-Thai ) of the Arizona Sexual Experiences Scale ( ASEX ) . METHOD The validity and reliability of ASEX-Thai were ass... |
5 | 24,417,824 | Preoperative carbohydrate drinks significantly improved insulin resistance and indices of patient comfort following surgery , especially hunger , thirst , malaise , anxiety and nausea .
No definite conclusions could be made regarding preservation of muscle mass .
Following ingestion of carbohydrate drinks , no adverse ... | INTRODUCTION Surgical stress in the presence of fasting worsens the catabolic state , causes insulin resistance and may delay recovery .
Carbohydrate rich drinks given preoperatively may ameliorate these deleterious effects .
A systematic review was undertaken to analyse the effect of preoperative carbohydrate loading ... | The effect on gastric pH and volume of 0 , 6 and 10 ml · kg−1 , of apple juice given 2.5 hours before surgery to children aged five to ten years was investigated in this prospect i ve , r and omized , single-blind study . Gastric contents were aspirated after induction of anaesthesia , and the volume measured . The pH ... |
6 | 28,416,626 | Conclusions — In observational studies , reinstitution of anticoagulation after ICH was associated with a lower risk of thromboembolic complications and a similar risk of ICH recurrence . | Background and Purpose — The safety and efficacy of restarting anticoagulation therapy after intracranial hemorrhage ( ICH ) remain unclear .
We performed a systematic review and meta- analysis to summarize the associations of anticoagulation resumption with the subsequent risk of ICH recurrence and thromboembolism . | Background : For patients who survive intracerebral haemorrhage ( ICH ) during treatment with oral anticoagulation ( OAC ) , the balance between the benefits and risks of restarting OAC is unclear . The decision to restart OAC or to start antiplatelet therapy in these patients therefore poses a dilemma for all physici... |
7 | 25,767,129 | "This meta- analysis found no evidence of an increased risk of suicide or attempted suicide , suicid(...TRUNCATED) | "OBJECTIVE To determine the risk of neuropsychiatric adverse events associated with use of varenicli(...TRUNCATED) | "Abstract Alcohol and nicotine dependence are common in schizophrenia . Varenicline is effective in(...TRUNCATED) |
8 | 26,949,760 | "Overall , the 5-year complication rates were low .\nThe most frequent complications were secondary (...TRUNCATED) | "OBJECTIVE The purpose of this systematic review was to compare the survival and complication rates (...TRUNCATED) | "This study prospect ively evaluated the clinical performance of computer-assisted design and comput(...TRUNCATED) |
9 | 21,474,812 | "Because of insufficient method ological quality of most prognostic studies , the predictive value o(...TRUNCATED) | "BACKGROUND AND PURPOSE Knowledge about robust and unbiased factors that predict outcome of activiti(...TRUNCATED) | "Background and Purpose — Several prognostic factors have been identified for outcome after stroke(...TRUNCATED) |
End of preview. Expand in Data Studio
No dataset card yet
- Downloads last month
- 13