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Dec 2

CueBench: Advancing Unified Understanding of Context-Aware Video Anomalies in Real-World

How far are deep models from real-world video anomaly understanding (VAU)? Current works typically emphasize on detecting unexpected occurrences deviated from normal patterns or comprehending anomalous events with interpretable descriptions. However, they exhibit only a superficial comprehension of real-world anomalies, with limited breadth in complex principles and subtle context that distinguish the anomalies from normalities, e.g., climbing cliffs with safety gear vs. without it. To this end, we introduce CueBench, the first of its kind Benchmark, devoted to Context-aware video anomalies within a Unified Evaluation framework. We comprehensively establish an event-centric hierarchical taxonomy that anchors two core event types: 14 conditional and 18 absolute anomaly events, defined by their refined semantics from diverse contexts across 174 scenes and 198 attributes. Based on this, we propose to unify and benchmark context-aware VAU with various challenging tasks across recognition, temporal grounding, detection, and anticipation. This also serves as a rigorous and fair probing evaluation suite for generative-discriminative as well as generalized-specialized vision-language models (VLMs). To address the challenges underlying CueBench, we further develop Cue-R1 based on R1-style reinforcement fine-tuning with verifiable, task-aligned, and hierarchy-refined rewards in a unified generative manner. Extensive results on CueBench reveal that, existing VLMs are still far from satisfactory real-world anomaly understanding, while our Cue-R1 surpasses these state-of-the-art approaches by over 24% on average.

  • 9 authors
·
Nov 1

ProteinRPN: Towards Accurate Protein Function Prediction with Graph-Based Region Proposals

Protein function prediction is a crucial task in bioinformatics, with significant implications for understanding biological processes and disease mechanisms. While the relationship between sequence and function has been extensively explored, translating protein structure to function continues to present substantial challenges. Various models, particularly, CNN and graph-based deep learning approaches that integrate structural and functional data, have been proposed to address these challenges. However, these methods often fall short in elucidating the functional significance of key residues essential for protein functionality, as they predominantly adopt a retrospective perspective, leading to suboptimal performance. Inspired by region proposal networks in computer vision, we introduce the Protein Region Proposal Network (ProteinRPN) for accurate protein function prediction. Specifically, the region proposal module component of ProteinRPN identifies potential functional regions (anchors) which are refined through the hierarchy-aware node drop pooling layer favoring nodes with defined secondary structures and spatial proximity. The representations of the predicted functional nodes are enriched using attention mechanisms and subsequently fed into a Graph Multiset Transformer, which is trained with supervised contrastive (SupCon) and InfoNCE losses on perturbed protein structures. Our model demonstrates significant improvements in predicting Gene Ontology (GO) terms, effectively localizing functional residues within protein structures. The proposed framework provides a robust, scalable solution for protein function annotation, advancing the understanding of protein structure-function relationships in computational biology.

  • 3 authors
·
Sep 1, 2024